IDSA guidelines classification scheme

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Strength of Recommendations

Class A

Good evidence to support a recommendation for or against use.

Class B

Moderate evidence to support a recommendation for or against use.

Class C

Poor evidence to support a recommendation.

Quality of Evidence

Level of Evidence I

Evidence from ≥1 properly randomized, controlled trial.

Level of Evidence II

Evidence from ≥1 well-designed clinical trial, without randomization; from cohort or case-controlled analytic studies (preferably from >1 center); from multiple time-series; or from dramatic results from uncontrolled experiments.

Level of Evidence III

Evidence from opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees.

Applying Strength of Recommendations and Quality of Evidence

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IDSA Updated Guidelines Classification Scheme 2016

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