Bacterial meningitis lumbar puncture
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Bacterial meningitis Microchapters |
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Diagnosis |
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Treatment |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]
Overview
Lumbar puncture
Indications of lumbar puncture
Findings of lumbar puncture in bacterial meningitis
Following CSF findings may suggest bacterial meningitis:[1][2]
- A pressure of over 180 mmH2O [1][2][3]
- CSF cell count in 1000s.
- Granulocytes > lymphocytest
- Elevated protein may range between 100-500mg/dl
- Glucose ratio(CSF/plasma)<0.3
- CSF lactate >2.1mmol/l[3]
Contraindications of lumbar puncture
References
- ↑ 1.0 1.1 de Gans J, van de Beek D, European Dexamethasone in Adulthood Bacterial Meningitis Study Investigators (2002). "Dexamethasone in adults with bacterial meningitis". N Engl J Med. 347 (20): 1549–56. doi:10.1056/NEJMoa021334. PMID 12432041. Review in: ACP J Club. 2003 May-Jun;138(3):60
- ↑ 2.0 2.1 Durand ML, Calderwood SB, Weber DJ, Miller SI, Southwick FS, Caviness VS; et al. (1993). "Acute bacterial meningitis in adults. A review of 493 episodes". N Engl J Med. 328 (1): 21–8. doi:10.1056/NEJM199301073280104. PMID 8416268.
- ↑ 3.0 3.1 Huy NT, Thao NT, Diep DT, Kikuchi M, Zamora J, Hirayama K (2010). "Cerebrospinal fluid lactate concentration to distinguish bacterial from aseptic meningitis: a systemic review and meta-analysis". Crit Care. 14 (6): R240. doi:10.1186/cc9395. PMC 3220013. PMID 21194480.