Cystitis laboratory findings
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Steven C. Campbell, M.D., Ph.D.
Overview
Presence of signs and symptoms of cystitis like dysuria, noctuira, frequency and urgency increase the probability of confirmation of Cystitis as the diagnosis. Laboratory tests used in the diagnosis and confirmation of cystitis include urinalysis and urine culture. Laboratory findings consistent with the diagnosis of cystitis include pyuria and either white blood cells (WBCs) or red blood cells (RBCs) on urinalysis and a positive urine culture.[1]
Laboratory Findings
Urinalysis
- A urinalysis commonly reveals white blood cells (WBCs) or red blood cells (RBCs).
- Pyuria: >5-10 WBC/hpf or 27 WBC/microliter
- Dipstick:
- Nitrate reductase test: The nitrate reductase test is a test to differentiate between bacteria based on their ability or inability to reduce nitrate (NO3) to nitrite (NO2) using anaerobic respiration.
- Leukocyte esterase: Leukocyte esterase (LE) is a urine test for the presence of white blood cells and other abnormalities associated with infection.
Urine Culture
- A urine culture (clean catch) or catheterized urine specimen may be performed to determine the type of bacteria in the urine and the appropriate antibiotic for treatment.
- Most patients with urinary tract infection will have > 100,000 colonies of organism.
Bacterial Culture
Viral Culture
Fungal Culture
References
- ↑ Shaikh N, Morone NE, Lopez J, Chianese J, Sangvai S, D'Amico F; et al. (2007). "Does this child have a urinary tract infection?". JAMA. 298 (24): 2895–904. doi:10.1001/jama.298.24.2895. PMID 18159059.