Tropical sprue differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Tropical sprue must be differentiated from celiac disease, chronic diarrhea, Clonorchiasis, traveler's diarrhea, and whipworm.
Differentiating Tropical sprue from other Diseases
| Causes | Pathophysiology and Histology | Acute diarrhea | Traveller's diarrhea | Chronic diarrhea | Malabsorption | Steatorrhoea | Diagnosis | Confirmatory tests | Associations |
|---|---|---|---|---|---|---|---|---|---|
| Infectious |
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Chronic diarrhea
- Tropical sprue
- Ulcerative Colitis,
- Crohn's disease
- Diarrhea, chronic responsive to antiparasitic drugs
- Diarrhea, chronic unknown
- Inflammatory bowel disease, new onset post-travel (Crohn or ulcerative colitis)
- Irritable bowel syndrome
- Irritable bowel syndrome, post infectious
- Lactose intolerance, post infectious
- Malabsorption
Acute diarrhea
- E. coli
- Clostridium difficile-associated disease
- Campylobacter
- Cholera (toxigenic Vibrio cholerae)
- Cryptosporidium
- Cyclospora
- Diarrhea, acute bacterial
- Diarrhea, acute parasitic
- Diarrhea, acute unspecified
- Diarrhea, acute viral
- Dysentery, acute unspecified
- Entamoeba histolytica, ameba
- E. histolytica, diarrhea
- E. histolytica, dysentery
- Food poisoning
- Gastroenteritis
- Giardia
- Isospora
- Noncholera Vibrio
- Salmonella, other
- Shiga toxin-producing Escherichia coli
- Shigella, S. boydii
- Shigella, S. dysenteriae
- Shigella, S. flexneri
The following diseases have a similar presentation to tropical sprue.
- Celiac Disease
- Chronic diarrhea
- Clonorchiasis
- Traveler's diarrhea
- Whipworm