Pyogenic liver abscess differential diagnosis

Liver abscess Main Page
Pyogenic liver abscess Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating pyogenic liver abscess from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X Ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Pyogenic liver abscess differential diagnosis On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Pyogenic liver abscess differential diagnosis All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Pyogenic liver abscess differential diagnosis
CDC on Pyogenic liver abscess differential diagnosis
Pyogenic liver abscess differential diagnosis in the news
Blogs on Pyogenic liver abscess differential diagnosis
Directions to Hospitals Treating Type chapter name here
Risk calculators and risk factors for Pyogenic liver abscess differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Overview

Pyogenic liver abscess must be differentiated from other diseases with similar presentation such as amoebic liver abscess, fungal liver abscess, echinococcal (hydatid) cyst and malignancy (hepatocelluar carcinoma or metastasis).

Differential Diagnosis

Pyogenic liver abscess must be differentiated from:

Disease	Causes	symptoms											Lab Findings	Imaging Findings	Other Findings
		Fever	Pain		cough	Hepatomegaly	Jaundice	Weight loss	Anorexia	Diarrhoea or Dysentry	Nausea and vomiting	Stool
			Abdominal pain (right upper quadrant pain)	Pleuritic pain
Amoebic liver abscess	Entamoeba histolytica	✔✔✔	✔✔✔	✔/✘	✔	✔/✘	✔ (late stages)	✔ (late stages)	✔	✔	✔		Hypoalbuminemia ✔		Respond well to chemotherapy and rarely require drainage Marked male predominance More common in developing countries
Pyogenic liver abscess	Bacteria Gram-positive aerobes Gram-negative enterics Anaerobic organisms Acid fast bacilli	✔	✔	✔✔	✔✔		✔✔✔	✔ (acute loss)	✔		✔	Pale/dark	Hypoalbuminemia ✔✔✔		Abnormal pulmonary findings Diabetes mellitus increases the risk Medical-surgical approach is indicated More common in developed countries
Fungal liver abscess	Candida species	✔	✔		✔	✔	✔	✔	✔	✔	✔				Less common
Echinococcal (hydatid) cyst	Echinococcus granulosus		✔		✔		✔	✔	✔						Blood or liquid from the ruptured cyst may be coughed up
Malignancy (Hepatocellular carcinoma/Metastasis)	Hepatitis B and C Aflatoxins Alcohol Heamochromatosis Alpha 1 antitrypsin deficiency Non alcoholic fatty liver disease		✔ (uncommon)			✔	✔								Other symptoms: Splenomegaly Variceal bleeding Ascites Spider nevi Asterixis