Hypoparathyroidism causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Charmaine Patel, M.D. [2] Luke Rusowicz-Orazem, B.S.
Overview
Causes
Hypoparathyroidism can have a number of divergent causes:
- Removal of the parathyroid glands in thyroid surgery (thyroidectomy) is a recognised cause. It is now uncommon, as surgeons generally spare them during the procedure after identifying them.
- Autoimmune invasion and destruction is the most common non-surgical cause. It can occur as part of autoimmune polyendocrine syndromes.
- Hemochromatosis can lead to iron accumulation and consequent dysfunction of a number of endocrine organs, including the parathyroids.
- Absence or dysfunction of the parathyroid glands is one of the components of chromosome 22q11 microdeletion syndrome (other names: DiGeorge syndrome, Schprintzen syndrome, velocardiofacial syndrome).
- Magnesium deficiency
- Some very rare diseases
- Idiopathic (of unknown cause), occasionally familial
Life Threatening Causes
Common Causes
- Autoimmune polyendocrine syndrome
- Thyroidectomy
- Polyendocrine deficiency syndrome
- Polyglandular autoimmune syndrome
- Hemochromatosis
- Magnesium deficiency
- Velocardiofacial syndrome
Causes by Organ System
Causes in Alphabetical Order
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