Sandbox:Aditya

Typhus fever

• Typhus is defined as a group of diseases caused by bacteria that are spread to humans by fleas, lice, and chiggers.
• Typhus fevers include scrub typhus, murine typhus, and epidemic typhus.
• Chiggers spread scrub typhus, fleas spread murine typhus, and body lice spread epidemic typhus.
• The most common symptoms are fever, headaches, and sometimes rash.

Pathophysiology

• Scratching a louse-bite site allows the rickettsia-laden excrement to be inoculated into the bite wound.
• The rickettsia travel to the bloodstream, and rickettsemia develops.
• The major pathology is caused by a vasculitis and its complications.