Ulcerative colitis pathophysiology

Ulcerative colitis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pathophysiology

• Ulcerative colitis is characterized by inflammation of the mucosa which is diffuse and primarily confined to the colon.
• The disease can extend proximally in a continuous, circular and uniform manner.

Pathogenesis

The pathogenesis of ulcerative colitis includes:

• Dysregulation of cytokine function