Chronic diarrhea screening
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omodamola Aje B.Sc, M.D. [2]
Overview
There are certain features which if present in a patient complaining of diarrhea for over 4 weeks require further evaluation. Some of the screening modalities include, radiographic imaging studies[1], endoscopy/enteroscopy/capsule enteroscopy[2], histopathology of the small bowel and colon[3], bacteriology/microbiology[4], serological testing and chemical analysis of stool[5].
Screening
There are certain features which if present in a patient complaining of diarrhea for over 4 weeks require further evaluation. these include:
- Rectal bleeding[6]
- Weight loss
- Age > 50 years[7]
- Pain[8]
- Associated psychological factors
- Somatization[9]
- Dietary causes of diarrhea[1]
References
- ↑ 1.0 1.1 Hammer HF, Fine KD, Santa Ana CA, Porter JL, Schiller LR, Fordtran JS (1990). "Carbohydrate malabsorption. Its measurement and its contribution to diarrhea". J Clin Invest. 86 (6): 1936–44. doi:10.1172/JCI114927. PMC 329829. PMID 2254453.
- ↑ Balaban DV, Popp A, Vasilescu F, Haidautu D, Purcarea RM, Jinga M (2015). "Diagnostic yield of endoscopic markers for celiac disease". J Med Life. 8 (4): 452–7. PMC 4656951. PMID 26664469.
- ↑ Le Berre N, Heresbach D, Kerbaol M, Caulet S, Bretagne JF, Chaperon J; et al. (1995). "Histological discrimination of idiopathic inflammatory bowel disease from other types of colitis". J Clin Pathol. 48 (8): 749–53. PMC 502803. PMID 7560203.
- ↑ Khanna S, Pardi DS, Rosenblatt JE, Patel R, Kammer PP, Baddour LM (2012). "An evaluation of repeat stool testing for Clostridium difficile infection by polymerase chain reaction". J Clin Gastroenterol. 46 (10): 846–9. doi:10.1097/MCG.0b013e3182432273. PMID 22334221.
- ↑ Eherer, Andreas J.; Fordtran, John S. (1992). "Fecal osmotic gap and pH in experimental diarrhea of various causes". Gastroenterology. 103 (2): 545–551. doi:10.1016/0016-5085(92)90845-P. ISSN 0016-5085.
- ↑ Halfdanarson TR, Litzow MR, Murray JA (2007). "Hematologic manifestations of celiac disease". Blood. 109 (2): 412–21. doi:10.1182/blood-2006-07-031104. PMC 1785098. PMID 16973955.
- ↑ Olesen M, Eriksson S, Bohr J, Järnerot G, Tysk C (2004). "Microscopic colitis: a common diarrhoeal disease. An epidemiological study in Orebro, Sweden, 1993-1998". Gut. 53 (3): 346–50. PMC 1773978. PMID 14960513.
- ↑ Tillisch K, Labus JS, Naliboff BD, Bolus R, Shetzline M, Mayer EA; et al. (2005). "Characterization of the alternating bowel habit subtype in patients with irritable bowel syndrome". Am J Gastroenterol. 100 (4): 896–904. doi:10.1111/j.1572-0241.2005.41211.x. PMID 15784038.
- ↑ . doi:10.1016/j.cgh.2006.11.024 showArticle Info Check
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