Hypoglycemia surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Mohammed Abdelwahed M.D[2]
Overview
Surgical removal of the insulinoma is the treatment of choice and resection of metastatic liver disease.
Surgery
- Surgical removal of the insulinoma is the treatment of choice:[1]
- Enucleation of the insulinoma
- Partial distal pancreatectomy
- Distal subtotal pancreatectomy is recommended for patients with insulinoma related to MEN1.[2]
- Recurrence is more common in the patients with MEN1.
- Hepatic resection is indicated for the treatment of metastatic liver disease if general condition is good. Resection should be considered only for patients with a limited number of hepatic metastases.
References
- ↑ Service FJ, McMahon MM, O'Brien PC, Ballard DJ (1991). "Functioning insulinoma--incidence, recurrence, and long-term survival of patients: a 60-year study". Mayo Clin Proc. 66 (7): 711–9. PMID 1677058.
- ↑ Demeure MJ, Klonoff DC, Karam JH, Duh QY, Clark OH (1991). "Insulinomas associated with multiple endocrine neoplasia type I: the need for a different surgical approach". Surgery. 110 (6): 998–1004, discussion 1004-5. PMID 1684067.