Hashimoto's thyroiditis laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
Laboratory findings consistent with the diagnosis of Hashimoto's thyroiditis usually include increased thyroid stimulating hormone, decreased free T3 and free T4, and anti-thyroid peroxidase antibodies.
Laboratory Findings
Laboratory findings consistent with the diagnosis of Hashimoto's thyroiditis usually include increased Yhyroid stimulating hormone, decreased free T3 and free T4, and Anti-thyroid peroxidase anntibodies.[1]
Thyroid hormones
- Increased Thyroid-stimulating hormone (TSH)
- Decreased Free T3 and Free T4
- TSH may be decreased in the transient hyperthyroid state.[2]
Thyroid antibodies
- Anti-thyroid peroxidase antibodies (anti-TPO) (correlates with the disease severity)
- Anti-thyroglobulin antibodies (anti-Tg)
- Anti-microsomal antibodies can help obtain an accurate diagnosis.[3]
References
- ↑ Dong YH, Fu DG (2014). "Autoimmune thyroid disease: mechanism, genetics and current knowledge". Eur Rev Med Pharmacol Sci. 18 (23): 3611–8. PMID 25535130.
- ↑ Simmons, PJ (1998). "Antigen-presenting dendritic cells as regulators of the growth of thyrocytes: a role of interleukin-1beta and interleukin-6". Endocrinology. 139 (7): 3158–3186. doi:10.1210/en.139.7.3148. PMID 9645688.
- ↑ Giannini, AJ (1986). The Biological Foundations of Clinical Psychiatry. New Hyde Park, NY: Medical Examination Publishing Company. pp. 193–198. ISBN 0-87488-449-7.