Acromegaly historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Overview

Historical Perspective

Discovery

  • In 1567, Dr.  Johannes Wier was the first to describe a case of a giant female patient. Dr. Wier described the course of acromegaly in this patient in his article. Dr. Wier mentioned that she was of normal stature then she began to increase in height and size at age of fourteen. However, she had a normal good life. Dr. Wier also linked between the acromegaly and amenorrhea in this patient.[1]
  • In 1772, Dr. Nicolas Saucerotte reported a case which has a clinical presentation linked with acromegaly.
  • In 1864, Dr. Andrea Verga reported a case of acromegaly. Dr. Verga reported a patient whose disproportion big face.
  • In 1877, Dr. Henri Henrot also reported a case of acromegaly.
  • In 1886, Dr. Pierre Marie named the disease as acromegaly. Dr. Marie reported a patient presented with hypertrophied extremities and he linked between this presentation and acromegaly.

Landmark Events in the Development of Treatment Strategies

  • In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].

Impact on Cultural History

Famous Cases

References

  1. de Herder WW (2016). "The History of Acromegaly". Neuroendocrinology. 103 (1): 7–17. doi:10.1159/000371808. PMID 25572320.

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