Acromegaly physical examination
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
- Patients with [disease name] usually appear [general appearance]. Physical examination of patients with [disease name] is usually remarkable for [finding 1], [finding 2], and [finding 3].
- Common physical examination findings of [disease name] include [finding 1], [finding 2], and [finding 3].
- The presence of [finding(s)] on physical examination is diagnostic of [disease name].
- The presence of [finding(s)] on physical examination is highly suggestive of [disease name].
Physical Examination
Appearance of the Patient
- Patients with acromegaly usually appear tired.
Vital Signs
- Hypertension
Skin
- Thickening of the skin
- Skin tags
- Acne
- Acanthosis nigricans
- Hyperhidrosis
-
Description Template:Acanthosis nigricans in the axilla
HEENT
- Abnormalities of the head include frontal bossing
- Acral enlargement
- Visual deficits
- Hearing acuity may be reduced
- Facial tenderness
- Headache
- Macroglossia
- Prognathism
Lungs
- Obstruction of the upper airways
- Obstructive sleep apnea
Heart
Cardiac manifestations in acromegaly patients include the following:[1]
- Ventricular hypertrophy
- Diastolic heart failure (the most common cause of death)
- Diastolic and systolic dysfunction
- Arrhythmias
- Cardiomyopathy
Back
- Vertebral fractures
Neuromuscular
- Patient is usually oriented to persons, place, and time
- Osteopenia
- Osteoarthritis
- Joints effusion, swelling, and crepitus
- Acromegaly rosary: hypertrophy of the ribs and costochondral junction enlargement in the chest wall.[2]
- Muscle weakness
- Joint stiffness in late cases
- Malocclusion of patient jaw associated with temporomandibular joint tenderness
- Kyphoscoliosis[3]
- Paresthesia
- Cranial nerves palsy
- Carpal tunnel syndrome
Genitourinary
References
- ↑ López-Velasco R, Escobar-Morreale HF, Vega B, Villa E, Sancho JM, Moya-Mur JL; et al. (1997). "Cardiac involvement in acromegaly: specific myocardiopathy or consequence of systemic hypertension?". J Clin Endocrinol Metab. 82 (4): 1047–53. doi:10.1210/jcem.82.4.3876. PMID 9100571.
- ↑ Ibbertson HK, Manning PJ, Holdaway IM, Gamble G, Synek BJ (1991). "The acromegalic rosary". Lancet. 337 (8734): 154–6. PMID 1670798.
- ↑ Molitch ME (1992). "Clinical manifestations of acromegaly". Endocrinol Metab Clin North Am. 21 (3): 597–614. PMID 1521514.
- ↑ 4.0 4.1 Iuliano, Sherry L.; Laws, Edward R. (2014). "Recognizing the clinical manifestations of acromegaly: Case studies". Journal of the American Association of Nurse Practitioners. 26 (3): 136–142. doi:10.1002/2327-6924.12076. ISSN 2327-6886.