Acromegaly physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Patients with [disease name] usually appear [general appearance]. Physical examination of patients with [disease name] is usually remarkable for [finding 1], [finding 2], and [finding 3].
Common physical examination findings of [disease name] include [finding 1], [finding 2], and [finding 3].
The presence of [finding(s)] on physical examination is diagnostic of [disease name].
The presence of [finding(s)] on physical examination is highly suggestive of [disease name].

Cardiac manifestations in acromegaly patients include the following:^[1]^[2]

Patient is usually oriented to persons, place, and time
Osteopenia
Osteoarthritis
Joints effusion, swelling, and crepitus
Acromegaly rosary: hypertrophy of the ribs and costochondral junction enlargement in the chest wall.^[3]
Muscle weakness
Joint stiffness in late cases
Malocclusion of patient jaw associated with temporomandibular joint tenderness
Kyphoscoliosis^[4]
Paresthesia
Cranial nerves palsy
Carpal tunnel syndrome

↑ López-Velasco R, Escobar-Morreale HF, Vega B, Villa E, Sancho JM, Moya-Mur JL; et al. (1997). "Cardiac involvement in acromegaly: specific myocardiopathy or consequence of systemic hypertension?". J Clin Endocrinol Metab. 82 (4): 1047–53. doi:10.1210/jcem.82.4.3876. PMID 9100571.
↑ Martins JB, Kerber RE, Sherman BM, Marcus ML, Ehrhardt JC (1977). "Cardiac size and function in acromegaly". Circulation. 56 (5): 863–9. PMID 144034.
↑ Ibbertson HK, Manning PJ, Holdaway IM, Gamble G, Synek BJ (1991). "The acromegalic rosary". Lancet. 337 (8734): 154–6. PMID 1670798.
↑ Molitch ME (1992). "Clinical manifestations of acromegaly". Endocrinol Metab Clin North Am. 21 (3): 597–614. PMID 1521514.
↑ ^5.0 ^5.1 Iuliano, Sherry L.; Laws, Edward R. (2014). "Recognizing the clinical manifestations of acromegaly: Case studies". Journal of the American Association of Nurse Practitioners. 26 (3): 136–142. doi:10.1002/2327-6924.12076. ISSN 2327-6886.