Sheehan's syndrome natural history, complications and prognosis

Sheehan's syndrome Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

• Sheehan syndrome, if left untreated lead to mitral regurgitation, pericardial effusion and diminished LVM.
• Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
• Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.

Natural History, Complications, and Prognosis

Natural History

• Sheehan syndrome usually results in anterior pituitary shrinkage within 20 days followed by disappearance of pituitary tissue in 6-8 week resulting in hypopituitarism and empty sella syndrome.
• The symptoms of Sheehan's syndrome can develop during immediate post-puerperal period to years after delivery.
• If left untreated,lead to mitral regurgitation, pericardial effusion and diminished LVM, adrenal crisis, pituitay hypopituitarism and empty sella syndrome.

Complications

• Common complications of [disease name] include:
  • Adrenal crisis
  • Hypotension
  • Hypothyroidism
  • Menstrual irregularities
  • Empty sella syndrome

Prognosis

• Prognosis is generally good, and results in reversal of symptoms once respective hormones are being replaced.