Struma ovarii natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
- Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- If left untreated Struma ovarii may lead to thyrotoxicosis [1]
Complications
- The most feared complication of struma ovarii is thyrotoxicosis. Other complications include due to metastasis of stroma oavrii.[2]
Prognosis
- Prognosis is generally excellent under benign conditions, even in malignant cases, adjuvant iodine-131 ablation with surgical extirpation has excellent prognosis
- The 5/10/20-year mortality/survival rate of patients with Struma ovarii is approximately 96.7%, 94.3%, and 84.9%, respectively.
- In adults with differentiated thyroid cancer who are treated with high doses of radioiodine seem to have an excellent long-term prognosis. [3]
References
- ↑ Morrissey K, Winkel C, Hild S, Premkumar A, Stratton P (2007). "Struma ovarii coincident with Hashimoto's thyroiditis: an unusual cause of hyperthyroidism". Fertil. Steril. 88 (2): 497.e15–7. doi:10.1016/j.fertnstert.2006.11.095. PMC 2753978. PMID 17276434.
- ↑ Matsuda K, Maehama T, Kanazawa K (2001). "Malignant struma ovarii with thyrotoxicosis". Gynecol. Oncol. 82 (3): 575–7. doi:10.1006/gyno.2001.6315. PMID 11520159.
- ↑ Luo JR, Xie CB, Li ZH (2014). "Treatment for malignant struma ovarii in the eyes of thyroid surgeons: a case report and study of Chinese cases reported in the literature". Medicine (Baltimore). 93 (26): e147. doi:10.1097/MD.0000000000000147. PMC 4616397. PMID 25474425.