Toxic Adenoma overview
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Diagnosis |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
A toxic adenoma is a benign monoclonal tumor consisting of thyroid follicular cells, which produce excessive amounts of T 3 and/or T 4. In toxic adenomas, the excessive thyroid hormone autonomously produced can suppress the function of remaining thyroid tissue. Thus thyroid hormone production is no longer controlled by the hypothalamic-hypophyseal-thyroid axis, leading to thyroid hormone excess and the resulting clinical symptoms, signs, and potential complications.