Coccidioidomycosis historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

Coccidioidomycosis was first discovered for the time in 1892 by Alejandro Posadas (a medical student) along with his mentor and they grouped coccidioidomycosis under parasitic family. Emmet Rixford and T. Caspar Gilchrist coined the term coccidioidomycosis (resembling Coccidia) in 1896. William Ophüls and Herbert C. Moffitt described its dimorphic nature and defined it as a fungal etiology in 1900. C.immitis was investigated by the United States during the 1950s and 1960s as a potential biological weapon. It was never standardized, around beyond a few field trials, it was never weaponized.

Historical Perspective

  • In 1892, Alejandro Posadas (a medical student) along with his mentor, Robert Wernicke discovered coccidioidomycosis.[1] [2]
  • In 1896, Emmet Rixford and T. Caspar Gilchrist coined the term coccidioidomycosis (resembling Coccidia), they grouped coccidioidomycosis under parasitic family.
  • In 1900, William Ophüls and Herbert C. Moffitt described its dimorphic nature and defined it as a fungal etiology.
  • In 1914, Cooke discovered coccidioidin skin test using precipitin reaction for the first time in diagnosing coccidioidomycosis.
  • In 1929, Ernest Dickson described coccidioidomycosis as a lethal fungal disease.
  • In 1936, Ernest Dickson along with his student Myrnie Gifford discovered that coccidioidomycosis is the same "San Joaquin fever,” “Desert fever,” or “Valley fever" which was considered as a separate entity until then.
  • C. immitis was investigated by the United States during the 1950s and 1960s as a potential biological weapon. It was never standardized, around beyond a few field trials, it was never weaponized.

References

  1. Hirschmann, J. V. (2007). "The Early History of Coccidioidomycosis: 1892-1945". Clinical Infectious Diseases. 44 (9): 1202–1207. doi:10.1086/513202. ISSN 1058-4838.
  2. Brown J, Benedict K, Park BJ, Thompson GR (2013). "Coccidioidomycosis: epidemiology". Clin Epidemiol. 5: 185–97. doi:10.2147/CLEP.S34434. PMC 3702223. PMID 23843703.

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