Sandbox:Amd
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]
Adrenal Insufficiency
Disease | Clinical history/findings | Causes | Investigations/
Laboratory findings |
Medical management | Surgical management | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hypotension | Skin
pigmentation/ findings |
Fatigue | Anorexia/
Weightloss |
Abdominal pain | Muscle
weakness |
Other history/
findings |
Hypo
natremia |
Cortisol levels | Gold Standard | ||||
Differentiating amongst adrenal insufficiencies | |||||||||||||
Primary adrenal
insufficiency |
✔ | ✔ | ✔ | ✔ | ✔ | ✔ |
|
✔ | ↓ | Cosyntropin/ ACTH stimulation test | |||
Secondary adrenal
insufficiency |
± | -– | ✔ | ✔ | -– |
|
|
-– | Normal | Cosyntropin/ ACTH stimulation test | |||
Acute adrenal insufficiency | ↓↓ | ± | ✔ | ✔ | ✔ | ± |
|
|
✔ |
|
|||
Differentiating Adrenal Insufficiency from other diseases | |||||||||||||