Thyroid nodule history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

History and Symptoms

History

  • The presence of symptoms
  • A change in nodule size
  • Previous head or neck radiation exposure
    • Childhood irradiation associated with high risk of malignancy
  • Family history
    • Thyroid diseases
    • Thyroid cancer syndromes
    • Endocrine diseases (e.g. multiple endocrine neoplasia type 2 [MEN2], familial adenomatous polyposis, or Cowden syndrome)
  • History of neck pain
  • a sudden increase in the size of a neck lump
    • Raise the concern of malignancies and hemorrhagic thyroid cysts
  • Progressive voice change or hoarseness
    • May be associated with an invasive tumor

Symptoms

  • Dysphagia or anterior neck discomfort
    • May indicate a malignant tumor
    • Rarely seen in benign tumors
    • Choking sensation
    • Inability to lie flat

References

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