Hemolytic anemia history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Shyam Patel [2]
Overview
The symptoms of hemolysis mostly relate to (1) red blood cell loss and (2) release of hemoglobin and its breakdown products into the circulation. The breakdown products of hemoglobin will accumulate in the blood causing jaundice and be excreted in the urine causing the urine to become dark brown in color.
Symptoms
Some of the symptoms include[1]:
- Chills
- Dark urine
- Early satiety from enlarged spleen
- Fatigue
- Fever
- Pale skin color (pallor)
- Palpitations from elevated heart rate
- Shortness of breath
- Yellow skin color (jaundice)
Past Medical History
Certain aspects of the medical history can suggest a cause for hemolysis.
- Presence of prosthetic heart valve
- Presence of other comorbidities like chronic lymphocytic leukemia
- Presence of autoimmune conditions
- Use of drugs
- Consumption of fava beans
References
- ↑ Packman CH (2015). "The Clinical Pictures of Autoimmune Hemolytic Anemia". Transfus Med Hemother. 42 (5): 317–24. doi:10.1159/000440656. PMC 4678314. PMID 26696800.