Thalassemia epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]
Overview
Epidemiology and Demographics
Prevalence
The estimated prevalence of thalassemias is 16% in people from Cyprus, 3-14% in Thailand, and 3-8% in populations from India, Pakistan, Bangladesh, Malaysia and China. There are also prevalences in descendants of people from Latin America, and Mediterranean countries (e.g. Spain, Portugal, Italy, Greece and others). A very low prevalence has been reported from people in Africa (0.9%), with those in northern Africa having the highest prevalence, and northern Europe (0.1%).(4)
Race
- The carrier rate of beta-thalassemia in Cyprus is estimated to be 12,000 to 15,000 per 100,000 persons.[1]
- The carrier rate of beta-thalassemia in Greece is estimated to be 7,400 per 100,000 persons.[1]
- The carrier rate of beta-thalassemia in Turkey is estimated to be 600 to 13,000 per 100,000 persons.[1]
- In Turkey, approximately 1.6 million people (of 80 million) have thalassemia trait.
- In Turkey, approximately 5,500 people are homozygous for thalassemia.
References
- ↑ 1.0 1.1 1.2 De Sanctis V, Kattamis C, Canatan D, Soliman AT, Elsedfy H, Karimi M; et al. (2017). "β-Thalassemia Distribution in the Old World: an Ancient Disease Seen from a Historical Standpoint". Mediterr J Hematol Infect Dis. 9 (1): e2017018. doi:10.4084/MJHID.2017.018. PMC 5333734. PMID 28293406.