Chronic pancreatitis medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
The goals of management are:
- Pain control
- Management of pancreatic insufficiency by pancreatic enzyme replacement
- Management of complications[1]
Pain management:
Pain is managed in a stepwise approach of
- General recommendations
- Pancreatic enzyme replacement
- Analgesics
- Other invasive procedures
General recommendations:
Most of the patients usually improve following the general recommendations with only a few requiring analgesics.
(a) Smoking cessation:
(b) Cessation of alcohol intake:
(c) Small meals and hydration
Pancreatic Enzyme Supplementation:
Analgesics:
Antioxidants:
Specialized approaches:
(a) Celiac nerve block
(b) Endoscopic therapy
(c) Extracorporeal shock wave lithotripsy
(d) Radiation
Management of Steatorrhea:
(a) Dietary modification
(b) Lipase supplementation
(c) Vitamin supplementation
(d) Medium chain triglycerides
Management of glucose intolerance:
Management of other pancreatic complications:
References
- ↑ Callery MP, Freedman SD (2008). "A 21-year-old man with chronic pancreatitis". JAMA. 299 (13): 1588–94. doi:10.1001/jama.299.9.jrr80001. PMID 18319401.