Budd-Chiari syndrome history and symptoms
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Overview
The hallmark of Budd-Chiari syndrome is a triad of right upper quadrant abdominal pain, ascites, and hepatomegaly. Symptoms of Budd-Chiari syndrome include fever, abdominal pain, abdominal distension from ascites, lower extremity edema, jaundice, gastrointestinal bleeding from varices, portal hypertensive gastropathy, hepatic encephalopathy. Patients with subacute or chronic Budd-Chiari syndrome may be asymptomatic.
History and Symptoms
History and symptoms of Budd-Chiari syndrome include the following:[1][2][3]
History
The hallmark of Budd-Chiari syndrome is a triad of right upper quadrant abdominal pain, ascites, and hepatomegaly. A positive history of associated risk factors like myeloproliferative disorders, malignancy, paroxysmal nocturnal hemoglobinuria, antiphospholipid syndrome, factor V Leiden mutation, infections and benign liver lesions, oral contraceptives and pregnancy, hypercoagulable states, Behçet's syndrome, membranous webs.
Common Symptoms
- Symptoms of Budd-Chiari syndrome include:
- Fever
- Abdominal pain
- Abdominal distension from ascites
- Lower extremity edema
- Jaundice
- Gastrointestinal bleeding from varices or portal hypertensive gastropathy
- hepatic encephalopathy.
Less Common Symptoms
- Patients with subacute or chronic Budd-Chiari syndrome may be asymptomatic.
References
- ↑ Goel RM, Johnston EL, Patel KV, Wong T (2015). "Budd-Chiari syndrome: investigation, treatment and outcomes". Postgrad Med J. 91 (1082): 692–7. doi:10.1136/postgradmedj-2015-133402. PMID 26494427.
- ↑ Aydinli M, Bayraktar Y (2007). "Budd-Chiari syndrome: etiology, pathogenesis and diagnosis". World J. Gastroenterol. 13 (19): 2693–6. PMC 4147117. PMID 17569137.
- ↑ Marudanayagam R, Shanmugam V, Gunson B, Mirza DF, Mayer D, Buckels J, Bramhall SR (2009). "Aetiology and outcome of acute liver failure". HPB (Oxford). 11 (5): 429–34. doi:10.1111/j.1477-2574.2009.00086.x. PMC 2742613. PMID 19768148.