Chronic myelogenous leukemia physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]

Overview

Patients with chronic myelogenous leukemia are usually well-appearing. Physical examination of patients with chronic myelogenous leukemia is usually remarkable for skin bruising , fever, splenomegaly, and lymphadenopathy.

PMID:24729196/PMID:26434969

Patients with CML usually appear Splenomegaly. Hepatomegaly is less common. Lymphadenopathy and infiltration of skin or other tissues are uncommon.

Physical Examination

Common physical examination findings associated with chronic myelogenous leukemia include:

Appearance of the Patient

• Patients are usually well-appearing

Vital Signs

• Fever

Skin

• Bruises
• Petechiae
• Ulcers
• Vesicles

HEENT

• Decreased vision acuity

Neck

• Lymphadenopathy

Lungs

• Vesicular breath sounds
• Wheezing

Chest

• Axillary lymphadenopathy (usually painless)

Abdomen

• Splenomegaly

Genitourinary

• Inguinal lymphadenopathy (usually painless)
• Scrotal swelling

References

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