Chronic myelogenous leukemia risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
The most potent risk factor in the development of chronic myelogenous leukemia is ionizing radiation; for example, increased rates of CML were seen in people exposed to the atomic bombings of Hiroshima and Nagasaki. Other risk factors include formaldehyde, obesity, and smoking.[1][2]
Factors that increase the risk of chronic myelogenous leukemia:
- Older age
- Being male
- Radiation exposure, such as radiation therapy for certain types of cancer
Family history is not a risk factor
The chromosome mutation that leads to chronic myelogenous leukemia isn't passed from parents to offspring. This mutation is believed to be acquired, meaning it develops after birth.
Common Risk Factors
Less common Risk Factors
References
- ↑ Moloney WC (1987). "Radiogenic leukemia revisited". Blood. 70 (4): 905–8. PMID 3477299.
- ↑ Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/staging/?region=ab