Multiple myeloma historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Multiple myeloma was first discovered by Dr. Samuel Solly, a surgeon working in St.Thomas hospital in London in 1844.[1]
In 1847, Bence Jones reported his premortem findings in a short
note in the Lancet. A year later, he published a definitive paper on his laboratory findings with a detailed description of the technique he had used to analyze the urine. In 1850, MacIntyre summarized the case from the clinician’s point of view. At that time, albuminuria was the term used nonspecifically to mean proteinuria, while the term “Bence Jones protein” was first used by Fleischer in 1880. In 1898, Weber postulated that the bone marrow is the site of production of the Bence Jones protein. In 1917 and 1921, respectively, Jacobson and Walters recognized Bence Jones proteins
PMID:
- 29194778
Historical Perspective
- Multiple myeloma was first discovered by Dr. Samuel Solly, a surgeon working in St.Thomas hospital at London in 1844.[2]
- The Bence Jones protein was first discovered by Dr. Henry Bence Jones and found to be associated with multiple myeloma in 1850.[3]
References
- ↑ Moehler T, Goldschmidt H. Multiple Myeloma. Springer Science & Business Media; 2011. https://books.google.com/books?isbn=3540857729
- ↑ Moehler T, Goldschmidt H. Multiple Myeloma. Springer Science & Business Media; 2011. https://books.google.com/books?isbn=3540857729
- ↑ Kyle RA, Steensma DP (2011). "History of multiple myeloma". Recent Results Cancer Res. 183: 3–23. doi:10.1007/978-3-540-85772-3_1. PMID 21509678.