Myelofibrosis classification
|
Myelofibrosis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Myelofibrosis classification On the Web |
|
American Roentgen Ray Society Images of Myelofibrosis classification |
|
Risk calculators and risk factors for Myelofibrosis classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2], Sujit Routray, M.D. [3]
Overview
Myelofibrosis is subclassified into primary and secondary types with the primary type being the more common and a high proportion of the cases resulting from mutations in the Janus kinase 2 (JAK2) gene. It can be secondary to a variety of malignant, non-malignant, and hematologic conditions. It can also be secondary to infections, toxins, and autoimmune diseases.
Classification
Based on the origin, myelofibrosis may be classified into two subtypes: primary and secondary.[1]
- Primary myelofibrosis indicates that the disease is of unknown or spontaneous origin.
- Secondary myelofibrosis develops secondary to polycythemia vera, essential thrombocythaemia, leukemia, or lymphoma.
References
- ↑ Classification of myelofibrosis. Dr Henry Knipe and Dr Yuranga Weerakkody et al. Radiopaedia 2016. http://radiopaedia.org/articles/myelofibrosis. Accessed on March 14, 2016