Stomach cancer classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2] Mohammed Abdelwahed M.D[3]

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Overview

Gastric cancer classifications are Padova classification that classified gastric cancer into five types according to degree of dysplasia. Japanese classification subdivided gastric cancer according to the atypia degree to five types also.

Classification

Padova classification[1]

1. Negative for dysplasia

1.0 Normal

1.1 Reactive foveolar hyperplasia

1.2 Intestinal metaplasia (IM)

1.2.1 IM Complete type

1.2.2 IM Incomplete type

2. Indefinite for dysplasia

2.1 Foveolar hyperproliferation

2.2 Hyperproliferative IM

3. Non-invasive neoplasia (flat or elevated [synonym adenoma])

3.1 Low-grade

3.2 High-grade

3.2.1 Including suspicious for carcinoma without invasion (intreglandular)

3.2.2 Including carcinoma without invasion (intraglandular)

4. Suspicious for invasive carcinoma
5. Invasive adenocarcinoma

Japanese classification[2]

Category Definition
Group I Normal mucosa and benign lesions with no atypia
Group II Lesions showing atypia but diagnosed as benign (non-neoplastic)
Group III Borderline lesions between benign and malignant
Group V Lesions strongly suspected of carcinoma
Group V Carcinoma

References

  1. Rugge M, Correa P, Dixon MF, Hattori T, Leandro G, Lewin K; et al. (2000). "Gastric dysplasia: the Padova international classification". Am J Surg Pathol. 24 (2): 167–76. PMID 10680883.
  2. Japanese Gastric Cancer Association (2017). "Japanese gastric cancer treatment guidelines 2014 (ver. 4)". Gastric Cancer. 20 (1): 1–19. doi:10.1007/s10120-016-0622-4. PMC 5215069. PMID 27342689.

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