Portal vein thrombosis epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]
Overview
Epidemiology and Demographics
Incidence
- The incidence of portal vein thrombosis in cirrhotic patients is unknown.[1]
Prevalence
- The prevalence of portal vein thrombosis is approximately 5000-10,000 per 100,000 in overall cases of portal hypertension in developed counties and 40,000 per 100,000 in developing countries.[1][2]
- The prevalence of portal vein thrombosis is less than 1000 per 100,000 in patients with compensated cirrhosis, but is 8000-25000 per 100,000 in patients who are candidates for liver transplantation.[3][4][5]
Mortality rate
- The overall mortality rate of portal vein thrombosis is less than 10% except for patients with malignancy or cirrhosis.[1]
- The mortality rate of portal vein thrombosis in patients with malignancy or cirrhosis about 26%.[6]
- In patients with chronic portal vein thrombosis one-year survival alters from 80% to 95%, and 3-year survival varies from 75% to 90%.[7]
Age
- Patients of all age groups may develop portal vein thrombosis.[1]
- The incidence of portal vein thrombosis increases with age and it commonly affects individuals 66-70 years in men and 69-74 years in women.[2]
Race
- There is no racial predilection to portal vein thrombosis.
Gender
- Portal vein thrombosis affects men and women equally.[2]
Developed Countries
Developing Countries
References
- ↑ 1.0 1.1 1.2 1.3 Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L, Bombardieri G, De Cristofaro R, De Gaetano AM, Landolfi R, Gasbarrini A (2010). "Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment". World J. Gastroenterol. 16 (2): 143–55. PMC 2806552. PMID 20066733.
- ↑ 2.0 2.1 2.2 Ogren M, Bergqvist D, Björck M, Acosta S, Eriksson H, Sternby NH (2006). "Portal vein thrombosis: prevalence, patient characteristics and lifetime risk: a population study based on 23,796 consecutive autopsies". World J. Gastroenterol. 12 (13): 2115–9. PMC 4087695. PMID 16610067.
- ↑ Okuda K, Ohnishi K, Kimura K, Matsutani S, Sumida M, Goto N, Musha H, Takashi M, Suzuki N, Shinagawa T (1985). "Incidence of portal vein thrombosis in liver cirrhosis. An angiographic study in 708 patients". Gastroenterology. 89 (2): 279–86. PMID 4007419.
- ↑ Francoz C, Belghiti J, Vilgrain V, Sommacale D, Paradis V, Condat B, Denninger MH, Sauvanet A, Valla D, Durand F (2005). "Splanchnic vein thrombosis in candidates for liver transplantation: usefulness of screening and anticoagulation". Gut. 54 (5): 691–7. doi:10.1136/gut.2004.042796. PMC 1774501. PMID 15831918.
- ↑ Fimognari FL, Violi F (2008). "Portal vein thrombosis in liver cirrhosis". Intern Emerg Med. 3 (3): 213–8. doi:10.1007/s11739-008-0128-0. PMID 18274708.
- ↑ Chawla YK, Bodh V (2015). "Portal vein thrombosis". J Clin Exp Hepatol. 5 (1): 22–40. doi:10.1016/j.jceh.2014.12.008. PMC 4415192. PMID 25941431.
- ↑ Parikh, Sameer; Shah, Riddhi; Kapoor, Prashant (2010). "Portal Vein Thrombosis". The American Journal of Medicine. 123 (2): 111–119. doi:10.1016/j.amjmed.2009.05.023. ISSN 0002-9343.