Lactose intolerance other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]
Overview
Lactose intolerance test may be helpful in the diagnosis of lactose intolerance. Findings suggestive of lactose intolerance include bloating, diarrhea and abdominal pain and rising of blood glucose by less than 20 mg/dL after ingestion of lactose. Genetic test can also be used for diagnosis of primary lactase deficiency that is associated with CC genotype at -13.9 kb upstream of the lactase gene.
Other Diagnostic Studies
- Other diagnostic studies for lactose intolerance include:
- Lactose intolerance test: [1]
- 50 gr of oral lactose in adults ( 2 g/kg in children) is administerd and blood glucose levels are checked at 0, 60, and 120 minutes after ingestion of glucose.
- Presentation of symptoms such as bloating, diarrhea and abdominal pain and rising of blood glucose by less than 20 mg/dL (1.1 mmol/L) are diagnostic for lactose intolerance.
- This test is used less than lactose breath hydrogen test because it needs repeated measurements of blood glucose level
- False negative results:
- Diabetes
- Bacterial overgrowth
- 50 gr of oral lactose in adults ( 2 g/kg in children) is administerd and blood glucose levels are checked at 0, 60, and 120 minutes after ingestion of glucose.
- Genetic test for primary lactase deficiency [2]
- Lactose intolerance test: [1]
References
- ↑ Law D, Conklin J, Pimentel M (2010). "Lactose intolerance and the role of the lactose breath test". Am. J. Gastroenterol. 105 (8): 1726–8. doi:10.1038/ajg.2010.146. PMID 20686460.
- ↑ Rasinperä H, Savilahti E, Enattah NS, Kuokkanen M, Tötterman N, Lindahl H, Järvelä I, Kolho KL (2004). "A genetic test which can be used to diagnose adult-type hypolactasia in children". Gut. 53 (11): 1571–6. doi:10.1136/gut.2004.040048. PMC 1774274. PMID 15479673.