Lactose intolerance other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]
Overview
Lactose tolerance test may be helpful in the diagnosis of lactose intolerance. Findings suggestive of lactose intolerance include bloating, diarrhea and abdominal pain and rising of blood glucose by less than 20 mg/dL after ingestion of lactose. Genetic test can also be used for diagnosis of primary lactase deficiency that is associated with CC genotype at -13.9 kb upstream of the lactase gene.
Other Diagnostic Studies
Other diagnostic studies for lactose intolerance include:
Lactose tolerance test
- 50 gr of oral lactose in adults ( 2 g/kg in children) is administerd and blood glucose levels are checked at 0, 60, and 120 minutes after ingestion of glucose.
- False negative results:
Genetic test for primary lactase deficiency
- Acquired primary lactase deficiency is associated with a CC genotype at -13.9 kb upstream of the lactase gene and lactase persistence is related to TT genotype.[2]
References
- ↑ Law D, Conklin J, Pimentel M (2010). "Lactose intolerance and the role of the lactose breath test". Am. J. Gastroenterol. 105 (8): 1726–8. doi:10.1038/ajg.2010.146. PMID 20686460.
- ↑ 2.0 2.1 Rasinperä H, Savilahti E, Enattah NS, Kuokkanen M, Tötterman N, Lindahl H, Järvelä I, Kolho KL (2004). "A genetic test which can be used to diagnose adult-type hypolactasia in children". Gut. 53 (11): 1571–6. doi:10.1136/gut.2004.040048. PMC 1774274. PMID 15479673.