Aldehyde dehydrogenase 1 family, member L2 also known as ALDH1L2 is an enzyme that in humans is encoded by the ALDH1L2 gene .[1] [2] ALDH1L2 is the mitochondrial isoform of a similar enzyme, ALDH1L1 , which converts 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide.[3] [4]
References
↑ Strausberg RL, Feingold EA, Grouse LH, et al. (December 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
↑ Ota T, Suzuki Y, Nishikawa T, et al. (January 2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 . PMID 14702039 .
↑ Krupenko NI, Dubard ME, Strickland KC, Moxley KM, Oleinik NV, Krupenko SA. "ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase. " J Biol Chem. 2010 Jul 23;285(30):23056-63.
↑ Strickland KC, Krupenko NI, Dubard ME, Hu CJ, Tsybovsky Y, Krupenko SA. "Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahdyrofolate dehydrogenase. " Chem Biol Interact. 2011 May 30;191(1-3):129-36.
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