DRG2

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
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RefSeq (protein)

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Developmentally-regulated GTP-binding protein 2 is a protein that in humans is encoded by the DRG2 gene.[1][2][3]

The DRG2 gene encodes the developmentally regulated GTP-binding protein 2, a name derived from the fact that it shares significant similarity to known GTP-binding proteins. DRG2 was identified because it is expressed in normal fibroblasts but not in SV40-transformed fibroblasts. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17.[3]

References

  1. Schenker T, Trueb B (Jun 1998). "Assignment of the gene for a developmentally regulated GTP-binding protein (DRG2) to human chromosome bands 17p13→p12 by in situ hybridization". Cytogenet Cell Genet. 79 (3–4): 274–5. doi:10.1159/000134741. PMID 9605870.
  2. Schenker T, Lach C, Kessler B, Calderara S, Trueb B (Nov 1994). "A novel GTP-binding protein which is selectively repressed in SV40 transformed fibroblasts". J Biol Chem. 269 (41): 25447–53. PMID 7929244.
  3. 3.0 3.1 "Entrez Gene: DRG2 developmentally regulated GTP binding protein 2".

Further reading