Gallbladder cancer classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
Gallbladder cancer may be classified according to WHO into various subtypes and are as follows
Classification
Gallbladder carcinoma may be classified according to histology into following subtypes
SUBTYPE |
FEATURES |
| Adenocarcinoma | Sheets, cohesive fragments, acini, and mucin |
| Papillary adenocarcinoma | Pleomorphism and papillary fragments with vascular core |
| Mucinous adenocarcinoma | Single cells or cluster and extracellular mucin |
| Signet ring cell carcinoma | Intracellular mucin with signet ring cells |
| Adenosquamous carcinoma | Mixture of glandular and squamous components |
| Squamous cell carcinoma | Necrosis, tadpole cells and atypical keratinized cells |
| Neuroendocrine carcinoma | Salt and pepper chromatin,anisonucleosis and rosettes |
| Small cell carcinoma | Absent cytoplasm, Smudge cells, and mitoses |
| Undifferentiated carcinoma | Pleomorphic cells, abundant necrosis |