Barrett's esophagus causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amresh Kumar MD [2]

Overview

Barrett's Oesophagus is commonly caused by Gastroesophageal reflux disease.

Causes

Gastroesophageal reflux disease (GERD)

There are several anatomo-physiologic abnormalities that may contribute to GERD

• Hypersecretion of gastric acid.
• Decreased concentration of epidermal growth factor in salivary secretions.
• Diminished esophageal pain sensitivity.
• Poor contraction of the esophagus.
• Decreased muscle tone of the lower esophageal sphincter.