Sialolithiasis differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].

OR

[Disease name] must be differentiated from [[differential dx1], [differential dx2], and [differential dx3].

Differentiating Sialolithiasis from other Diseases

• Sialolithiasis must be differentiated from other diseases that cause swelling in salivary glands, such as acute bacterial sialadenitis, chronic bacterial sialadenitis, viral sialadenitis .
• [Disease name] must be differentiated from [[differential dx1], [differential dx2], and [differential dx3].

• As [disease name] manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. [Subtype name 1] must be differentiated from other diseases that cause [clinical feature 1], such as [differential dx1] and [differential dx2]. In contrast, [subtype name 2] must be differentiated from other diseases that cause [clinical feature 2], such as [differential dx3] and [differential dx4].

Preferred Table

Diseases	Symptoms and sign							Laboratory Findings				Other Findings
	Onset	Unilateral/Bilateral	Pain	Swelling	Tenderness	Purulent discharge	Common site of involvement	ESR	Leukocytosis	Lab Test 3	Lab Test 4
Salivary gland stone	Acute	Unilateral	+	+	+	-	Submandibular gland
Acute bacterial sialadenitis	Acute	Unilateral	+	+	+	+	Parotid
Chronic bacterial sialadenitis	Chronic	Unilateral	+	+	-	-	Parotid
Viral sialadenitis	Acute	Bilateral	+	+	+	-	Parotid
Human immunodeficiency virus	Acute	Bilateral	+	+	-	-	Parotid
Radiation sialadenitis	Acute	Unilateral	+	+	+	-	Depends on the treatment field
Sarcoidosis	Gradual	Bilateral	-	+	-	-	Parotid
Sjögren's syndrome	Gradual	Bilateral	+/-	+	-	-	Parotid or submandibular glands
Malnutrition	Gradual	Bilateral	+/-	+	-	-	Parotid
Salivary gland tumors	Subacute	Unilateral	-	+	-	-	Parotid