Sialolithiasis differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].

OR

[Disease name] must be differentiated from [[differential dx1], [differential dx2], and [differential dx3].

Differentiating Sialolithiasis from other Diseases

• Sialolithiasis must be differentiated from other diseases that cause swelling in salivary glands, such as acute bacterial sialadenitis, chronic bacterial sialadenitis, viral sialadenitis, human immunodeficiency virus, radiation, and systemic diseases such as, sarcoidosis, and sjögren's syndrome.

Differentiating Sialolithiasis from other Diseases table

Diseases	Symptoms and sign							Laboratory Findings				Other Findings
	Onset	Unilateral/Bilateral	Pain	Swelling	Tenderness	Purulent discharge	Common site of involvement	ESR	Leukocytosis	Lab Test 3	Lab Test 4
Salivary gland stone	Acute	Unilateral	+	+	+	-	Submandibular gland
Acute bacterial sialadenitis	Acute	Unilateral	+	+	+	+	Parotid
Chronic bacterial sialadenitis	Chronic	Unilateral	+	+	-	-	Parotid
Viral sialadenitis	Acute	Bilateral	+	+	+	-	Parotid
Human immunodeficiency virus	Acute	Bilateral	+	+	-	-	Parotid
Radiation sialadenitis	Acute	Unilateral	+	+	+	-	Depends on the treatment field
Sarcoidosis	Gradual	Bilateral	-	+	-	-	Parotid
Sjögren's syndrome	Gradual	Bilateral	+/-	+	-	-	Parotid or submandibular glands
Malnutrition	Gradual	Bilateral	+/-	+	-	-	Parotid
Salivary gland tumors	Subacute	Unilateral	-	+	-	-	Parotid