Polycythemia vera history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]; Shyam Patel [3]
Overview
People with polycythemia vera usually asymptomatic. Symptoms of polycythemia vera include headache, fatigue, and pruritis. The symptomatology is highly variable between patients. Some patients can present with a minimal symptom burden that does not result in any change in quality of life, and other patients can have severe symptom burden.
History and Symptoms
Symptoms of polycythemia vera are related to the consequences of excess red blood cells. These symptoms may include:[1][2][3][4][5][6][7][8]
- Especially after exposure to warm water
- Due to histamine release or prostaglandin production
- Present in approximately 40% of patients
- Tinnitis
- Blurred vision
- Malaise
- Loss of appetite
- Weight loss
- Shortness of breath
- Fatigue
- Dizziness
- Bleeding
- Due to increased susceptibility to infection with H. pylori
History[edit | edit source] Patients with [disease name]] may have a positive history of:
[History finding 1] [History finding 2] [History finding 3] Common Symptoms[edit | edit source] Common symptoms of polycythemia vera include:
[Symptom 1]
[Symptom 2]
[Symptom 3]
Less Common Symptoms[edit | edit source]
Less common symptoms of [disease name] include
[Symptom 1] [Symptom 2] [Symptom 3]
References
- ↑ Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia/leukemia/polycythemia-vera/?region=ab
- ↑ Steinman H, Kobza-Black A, Lotti T, Brunetti L, Panconesi E, Greaves M (1987). "Polycythaemia rubra vera and water-induced pruritus: blood histamine levels and cutaneous fibrinolytic activity before and after water challenge". Br J Dermatol. 116 (3): 329–33. PMID 3567071.
- ↑ Jackson N, Burt D, Crocker J, Boughton B (1987). "Skin mast cells in polycythaemia vera: relationship to the pathogenesis and treatment of pruritus". Br J Dermatol. 116 (1): 21–9. PMID 3814512.
- ↑ Fjellner B, Hägermark O (1979). "Pruritus in polycythemia vera: treatment with aspirin and possibility of platelet involvement". Acta Derm Venereol. 59 (6): 505–12. PMID 94209.
- ↑ Torgano G, Mandelli C, Massaro P, Abbiati C, Ponzetto A, Bertinieri G, Bogetto S, Terruzzi E, de Franchis R (2002). "Gastroduodenal lesions in polycythaemia vera: frequency and role of Helicobacter pylori". Br J Haematol. 117 (1): 198–202. PMID 11918555.
- ↑ van Genderen P, Michiels J (1997). "Erythromelalgia: a pathognomonic microvascular thrombotic complication in essential thrombocythemia and polycythemia vera". Semin Thromb Hemost. 23 (4): 357–63. PMID 9263352.
- ↑ Michiels J (1997). "Erythromelalgia and vascular complications in polycythemia vera". Semin Thromb Hemost. 23 (5): 441–54. PMID 9387203.
- ↑ Landolfi R, Ciabattoni G, Patrignani P, Castellana M, Pogliani E, Bizzi B, Patrono C (1992). "Increased thromboxane biosynthesis in patients with polycythemia vera: evidence for aspirin-suppressible platelet activation in vivo". Blood. 80 (8): 1965–71. PMID 1327286.