Restless legs syndrome historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
Historical Perspective
Discovery
- [Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event].
- The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
- In 1672, Sir Thomas Willis, a British anatomist and physician was the first to discover the leg discomfort experienced by some of his patients.[1]
- In a 1945 publication titled 'Restless Legs', Karl-Axel Ekbom described the disease and presented eight cases used for his studies.[2]
- In 1995 A large International Restless Legs Syndrome (RLS) Study Group has been formed. As its first task, the group has taken upon itself the role of defining the clinical features of the RLS. As minimal criteria for diagnosis, the group proposes the following four features: (a) desire to move the extremities, often associated with paresthesias/dysesthesias; (b) motor restlessness; (c) worsening of symptoms at rest with at least temporary relief by activity, and (d) worsening of symptoms in the evening or night. Other features commonly seen in RLS include sleep disturbance, periodic limb movements in sleep and similar involuntary movements while awake, a normal neurological examination in the idiopathic form, a tendency for the symptoms to be worse in middle to older age, and, in some cases, a family history suggestive of an autosomal dominant mode of inheritance.
Outbreaks
- There have been several outbreaks of [disease name], which are summarized below:
Landmark Events in the Development of Treatment Strategies
- In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].
Impact on Cultural History
Famous Cases
- The following are a few famous cases of disease name:
Overview
Earlier studies were done by Thomas Willis (1622-1675) and by Theodor Wittmaack.[3] Another early description of the disease and its symptoms were made by George Miller Beard (1839-1883).[3]
References
- ↑ Byrne R, Sinha S, Chaudhuri KR (2006). "Restless legs syndrome: diagnosis and review of management options". Neuropsychiatr Dis Treat. 2 (2): 155–64. PMC 2671772. PMID 19412460.
- ↑ Teive HA, Munhoz RP, Barbosa ER (2009). "Professor Karl-Axel Ekbom and restless legs syndrome". Parkinsonism Relat Disord. 15 (4): 254–7. doi:10.1016/j.parkreldis.2008.07.011. PMID 18829374.
- ↑ 3.0 3.1 Template:WhoNamedIt