Autoimmune hemolytic anemia historical perspective
|
Autoimmune hemolytic anemia Microchapters |
|
Differentiating Autoimmune hemolytic anemia from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Autoimmune hemolytic anemia historical perspective On the Web |
|
American Roentgen Ray Society Images of Autoimmune hemolytic anemia historical perspective |
|
Autoimmune hemolytic anemia historical perspective in the news |
|
Directions to Hospitals Treating Autoimmune hemolytic anemia |
|
Risk calculators and risk factors for Autoimmune hemolytic anemia historical perspective |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Assosciate Editor(s)-In-Chief: Prashanth Saddala M.B.B.S; Shyam Patel [2]
Overview
Historical Perspective
- In 1958, Leslie Zieve conducted a retrospective study on patients with alcoholic liver disease who had hemolytic anemia.[1]
- In 1968, Balcerzak confirmed the phenomenon of hemolytic anemia in conjunction with cholestatic jaundice and hypercholesterolemia.[1] This condition was known as Zieve syndrome, named after Leslie Zieve.
- In 1973, Playfair and Marshall-Clarke developed a murine model of autoimmune hemolytic anemia. In this murine model, the mice developed autoantibodies against their own red blood cells upon injection of rat red blood cells. The rat red blood cells triggered antibody production, since the rat antigens were foreign, but the antibodies also reacted against self antigens (murine antigens) also [2] Clinically, the mice developed anemia, elevated reticulocyte count, and positive direct antiglobulin test (Coomb's test). The mice had decreased survival.[2]
References
- ↑ 1.0 1.1 Liu MX, Wen XY, Leung YK, Zheng YJ, Jin MS, Jin QL; et al. (2017). "Hemolytic anemia in alcoholic liver disease: Zieve syndrome: A case report and literature review". Medicine (Baltimore). 96 (47): e8742. doi:10.1097/MD.0000000000008742. PMC 5708965. PMID 29381966.
- ↑ 2.0 2.1 Mqadmi A, Zheng X, Yazdanbakhsh K (2005). "CD4+CD25+ regulatory T cells control induction of autoimmune hemolytic anemia". Blood. 105 (9): 3746–8. doi:10.1182/blood-2004-12-4692. PMC 1895013. PMID 15637139.