Post-streptococcal glomerulonephritis medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]
Overview
Medical therapy
The mainstay of treatment is pharmacotherapy, however dietary therapy is useful for controlling edema and hypertension
Dietary therapy
- Low salt intake
- Low protein intake
- Water restrictions
Pharmacotherapy
- If streptococcal infection is still present, it should be treated with antibiotics[1]
- To control severe hypertension, following drugs can be used:
- Preferred regimen: Labetalol 0.5-2 mg/kg/h IV
- If refractory to labetalol then, Preferred regimen: Diazoxide or Nitroprusside 0.5-2 mcg/kg/min IV
- For mild to moderate hypertension:
- Preferred regimen: Furosemide 1-3 mg/kg PO q24h
- For treatment of rapidly progressive crescentic Acute post-streptococcal glomerulonephritis, following regimen is used
- Preferred regimen: Methylprednisolone