Polyarteritis nodosa other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Haritha Machavarapu, M.B.B.S.
Overview
EMG and nerve conduction studies can be done in cases of nerve involvement and help in nerve biopsy. Tissue biopsy (reveals inflammation in small arteries, called arteritis).
Other Diagnostic Studies
- EMG and nerve conduction studies can be done in cases of nerve involvement and help in nerve biopsy.[1]
- Tissue biopsy
- Biopsy is usually done from skin , testes, skeletal muscle or sural nerve.
- Biopsy can help to diagnose PAN even if creatine kinase elevation is not present.[2]
- Reveals inflammation in small arteries, called arteritis.
- If sample is taken from skin then it should be done at the edge and should include deep dermis and subcutaneous fat.[3]
- Biopsy often is done combined from nerve and muscle.[4]
References
- ↑ Lacomis D, Zivković SA (2007). "Approach to vasculitic neuropathies". J Clin Neuromuscul Dis. 9 (1): 265–76. doi:10.1097/CND.0b013e31815202b3. PMID 17989592. Unknown parameter
|month=ignored (help) - ↑ Hervier B, Durant C, Masseau A, Ponge T, Hamidou M, Mussini JM (March 2011). "Use of muscle biopsies for diagnosis of systemic vasculitides". J. Rheumatol. 38 (3): 470–4. doi:10.3899/jrheum.100390. PMID 21123326.
- ↑ Stone JH (October 2002). "Polyarteritis nodosa". JAMA. 288 (13): 1632–9. PMID 12350194.
- ↑ Griffin JW (November 2001). "Vasculitic neuropathies". Rheum. Dis. Clin. North Am. 27 (4): 751–60, vi. PMID 11723762.