Polycystic kidney disease epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2] Serge Korjian, Yazan Daaboul
Overview
ADPKD affects approximately 1 in 1000 individuals although prevalence varies according to countries and certain microsattelite regions with a heavy concentration of PKD mutations.
Epidemiology and Demographics
Incidence
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals in the United States.
- In 1957, the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
Prevalence
- The prevalence of autosomal dominant polycystic kidney disease (ARPKD) is approximately 100 - 250 per 100,000 individuals in the United States.[1][2][3]
- In 2013, the prevalence of autosomal dominant polycystic kidney disease was estimated to be 33 cases per 100,000 individuals in Germany.[4]
- In 1998, the prevalence of autosomal dominant polycystic kidney disease was estimated to be 25 cases per 100,000 individuals in Japan.[5]
- In 1996, the prevalence of autosomal dominant polycystic kidney disease was estimated to be 90 cases per 100,000 individuals in France.[6]
- In 1991, the prevalence of autosomal dominant polycystic kidney disease was estimated to be 41 cases per 100,000 individuals in United Kingdom.[7]
- In 1957, the prevalence of autosomal dominant polycystic kidney disease was estimated to be 100 cases per 100,000 individuals in Denmark.[8]
- The prevalence of autosomal recessive polycystic kidney disease (ARPKD) is approximately 5 per 100,000 children in the United States.[9]
Age
- Patients of all age groups may develop [disease name].
- The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
- ARPKD commonly affects infants and children.[9]
- [Chronic disease name] is usually first diagnosed among [age group].
- [Acute disease name] commonly affects [age group].
Race
- There is no racial predilection to autosomal dominant polycystic kidney disease.
Gender
- Autosomal dominant polycystic kidney disease affects men and women equally.[10]
References
- ↑ Iglesias CG, Torres VE, Offord KP, Holley KE, Beard CM, Kurland LT (May 1983). "Epidemiology of adult polycystic kidney disease, Olmsted County, Minnesota: 1935-1980". Am. J. Kidney Dis. 2 (6): 630–9. PMID 6846334.
- ↑ Gabow PA (July 1993). "Autosomal dominant polycystic kidney disease". N. Engl. J. Med. 329 (5): 332–42. doi:10.1056/NEJM199307293290508. PMID 8321262.
- ↑ Levy M, Feingold J (September 2000). "Estimating prevalence in single-gene kidney diseases progressing to renal failure". Kidney Int. 58 (3): 925–43. doi:10.1046/j.1523-1755.2000.00250.x. PMID 10972657.
- ↑ Neumann HP, Jilg C, Bacher J, Nabulsi Z, Malinoc A, Hummel B; et al. (2013). "Epidemiology of autosomal-dominant polycystic kidney disease: an in-depth clinical study for south-western Germany". Nephrol Dial Transplant. 28 (6): 1472–87. doi:10.1093/ndt/gfs551. PMID 23300259.
- ↑ Higashihara E, Nutahara K, Kojima M, Tamakoshi A, Yoshiyuki O, Sakai H; et al. (1998). "Prevalence and renal prognosis of diagnosed autosomal dominant polycystic kidney disease in Japan". Nephron. 80 (4): 421–7. PMID 9832641.
- ↑ Simon P, Le Goff JY, Ang KS, Charasse C, Le Cacheux P, Cam G (1996). "[Epidemiologic data, clinical and prognostic features of autosomal dominant polycystic kidney disease in a French region]". Nephrologie. 17 (2): 123–30. PMID 8838759.
- ↑ Davies F, Coles GA, Harper PS, Williams AJ, Evans C, Cochlin D (1991). "Polycystic kidney disease re-evaluated: a population-based study". Q J Med. 79 (290): 477–85. PMID 1946928.
- ↑ DALGAARD OZ (1957). "Bilateral polycystic disease of the kidneys; a follow-up of two hundred and eighty-four patients and their families". Acta Med Scand Suppl. 328: 1–255. PMID 13469269 Check
|pmid=value (help). - ↑ 9.0 9.1 Guay-Woodford LM, Desmond RA (May 2003). "Autosomal recessive polycystic kidney disease: the clinical experience in North America". Pediatrics. 111 (5 Pt 1): 1072–80. PMID 12728091.
- ↑ Torres VE, Harris PC, Pirson Y (2007). "Autosomal dominant polycystic kidney disease". Lancet. 369 (9569): 1287–301. doi:10.1016/S0140-6736(07)60601-1. PMID 17434405.