Myeloproliferative neoplasm classification
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Myeloproliferative Neoplasm Microchapters |
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Differentiating myeloproliferative neoplasm from other Diseases |
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Myeloproliferative neoplasm classification On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Myeloproliferative neoplasm may be classified according to the World Health Organization into eight subtypes: chronic myelogenous leukemia, chronic neutrophilic leukemia, polycythemia vera, primary myelofibrosis, essential thrombocythemia, chronic eosinophilic leukemia, mastocytosis, and myeloproliferative neoplasms, unclassifiable.[1]
Classification
| Disease | Cell of origin |
|---|---|
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Polycythemia vera |
Erythroid precursor |
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Essential thrombocythemia |
Megakaryocyte |
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Primary myelofibrosis |
Megakaryocyte |
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Chronic myeloid leukemia |
Common myeloid precursor |
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Chronic neutrophilic leukemia |
Neutrophil |
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Chronic eosinophilic leukemia |
Eosinophil |
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Myeloproliferative neoplasm, unclassifiable |
Variable |
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Mastocytosis |
Mast cell |
References
- ↑ Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A; et al. (2009). "The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes". Blood. 114 (5): 937–51. doi:10.1182/blood-2009-03-209262. PMID 19357394.