Myeloproliferative neoplasm chest x ray

Myeloproliferative Neoplasm Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2] Shyam Patel [3]

Overview

Chest x-ray may be helpful in the diagnosis of myeloproliferative neoplasm.

Chest X-Ray

There is no formal role for chest X-ray in the evaluation of myeloproliferative neoplasm. Findings on chest X-ray suggestive of myeloproliferative neoplasm include:

• Enlarged mediastinal lymph nodes
• Enlarged thymus gland
• Pleural effusion: Pleural effusions are commonly seen in patients receiving BCR-ABL tyrosine kinase inhibitors for chronic myeloid leukemia.
• Pneumonia: Pneumonia is commonly seen in patients who have neutropenic fever, which can develop from myelofibrosis or other myeloproliferative neoplasms.
• Pulmonary edema: This can develop if patients receive excess blood transfusions. Volume overload can result in alveolar edema and impaired oxygen exchange. Chest X-ray is useful in evaluating for pulmonary overload.

Findings on chest x-ray suggestive of chronic myelogenous leukemia include enlarged mediastinal lymph nodes, enlarged thymus gland, and pneumonia.