Multiple myeloma causes
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Multiple myeloma causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Recent studies have found that mutations of some oncogenes such as MYC develop early in the course of plasma cell tumors. Changes in the RAS genes are more often found in myeloma cells in the bone marrow after treatment, and changes in tumor suppressor genes like the gene for p53 are associated with spread to other organs.
Causes
- mutations of some oncogenes such as MYC
- mutations of some oncogenes such as RAS
- mutations of some tumor suppressor genes such as the gene for p53