Thrombotic thrombocytopenic purpura classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Saeedeh Kowsarnia M.D.[2]

Classification

• Hereditary: Insertions, deletions, missense, nonsense point mutations and splice site mutations of both alleles of ADAMS13 genes cause decrease in the amount and activity of the enzyme.

• Acquired: