Peripheral neuropathy history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
History and Symptoms
History
Patients with peripheral neuropathy may have a positive history of:[1][2][3][4][5]
- Metabolic disorders
- Long-standing illness
- Childhood clumsiness
- Unsteady gait and falls
- Neurological diseases
- Neurological diseases
- Occupational inorganic lead exposure
- Malignancy
Common Symptoms
The most common symptoms of peripheral neuropathy include:
- Gradual progressive numbness[6][7]
- Prickling or tingling in feet and [[[hands]][6][7]
- Burning pain in extremities[6]
- Extreme sensitivity to touch[6][7]
- Ataxia[8]
- Frequent falls[8]
- Muscle weakness or paralysis[6]
- Gastrointestinal symptoms:
- Constipation[9]
- Diarrhea[10]
- Early satiety[10]
- Nausea[11]
- Problems controlling bowel movements
- Swallowing problems[11]
- Abdomen distention[12]
- Vomiting[11]
- Cardiovascular symptoms:[13][14][15]
- Impaired heart rate
- Resting tachycardia
- Exercise intolerance
- Abnormal blood pressure regulation
- Orthostatic hypotension
- Heat intolerance and altered sweating[16]
- Urine incontinence:[17][18]
- Ocular symptoms:[19][20][21]
- Pain (usually from optic neuritis)
- Vision loss
- Visual field loss
- Loss of color vision
- Flashing lights
References
- ↑ Kelly JJ (2005). "Peripheral neuropathy: the importance of history and examination for correct diagnosis". Rev Neurol Dis. 2 (3): 150–3. PMID 16400316.
- ↑ Rubens O, Logina I, Kravale I, Eglîte M, Donaghy M (2001). "Peripheral neuropathy in chronic occupational inorganic lead exposure: a clinical and electrophysiological study". J Neurol Neurosurg Psychiatry. 71 (2): 200–4. PMC 1737511. PMID 11459892.
- ↑ Keller MP, Chance PF (1999). "Inherited peripheral neuropathy". Semin Neurol. 19 (4): 353–62. doi:10.1055/s-2008-1040850. PMID 10716658.
- ↑ Sharma CM, Sears M (1990). "Metabolic neuropathy". Clin Podiatr Med Surg. 7 (1): 97–105. PMID 2405988.
- ↑ Storstein A, Vedeler C (2001). "Neuropathy and malignancy: a retrospective survey". J Neurol. 248 (4): 322–7. PMID 11374098.
- ↑ 6.0 6.1 6.2 6.3 6.4 Marchettini P, Lacerenza M, Mauri E, Marangoni C (2006). "Painful peripheral neuropathies". Curr Neuropharmacol. 4 (3): 175–81. PMC 2430688. PMID 18615140.
- ↑ 7.0 7.1 7.2 Wolf SL, Barton DL, Qin R, Wos EJ, Sloan JA, Liu H; et al. (2012). "The relationship between numbness, tingling, and shooting/burning pain in patients with chemotherapy-induced peripheral neuropathy (CIPN) as measured by the EORTC QLQ-CIPN20 instrument, N06CA". Support Care Cancer. 20 (3): 625–32. doi:10.1007/s00520-011-1141-9. PMC 3329939. PMID 21479990.
- ↑ 8.0 8.1 Linnemann C, Tezenas du Montcel S, Rakowicz M, Schmitz-Hübsch T, Szymanski S, Berciano J; et al. (2016). "Peripheral Neuropathy in Spinocerebellar Ataxia Type 1, 2, 3, and 6". Cerebellum. 15 (2): 165–73. doi:10.1007/s12311-015-0684-6. PMID 26054379.
- ↑ Yamada E, Namiki Y, Takano Y, Takamine H, Inazumi K, Sasaki H; et al. (2018). "Clinical factors associated with the symptoms of constipation in patients with diabetes mellitus: A multicenter study". J Gastroenterol Hepatol. 33 (4): 863–868. doi:10.1111/jgh.14022. PMID 29048762.
- ↑ 10.0 10.1 Pfluecke C, Ulbrich S, Ibrahim K, Geiger KD, Strasser RH, Wunderlich C (2013). "Chronic diarrhea as the initial clinical manifestation of light-chain amyloidosis with cardiac involvement despite negative duodenal and rectal biopsies". Exp Clin Cardiol. 18 (2): 148–50. PMC 3718595. PMID 23940440.
- ↑ 11.0 11.1 11.2 Devigili G, Tugnoli V, Penza P, Camozzi F, Lombardi R, Melli G; et al. (2008). "The diagnostic criteria for small fibre neuropathy: from symptoms to neuropathology". Brain. 131 (Pt 7): 1912–25. doi:10.1093/brain/awn093. PMC 2442424. PMID 18524793.
- ↑ Krishnan B, Babu S, Walker J, Walker AB, Pappachan JM (2013). "Gastrointestinal complications of diabetes mellitus". World J Diabetes. 4 (3): 51–63. doi:10.4239/wjd.v4.i3.51. PMC 3680624. PMID 23772273.
- ↑ Pop-Busui R (2010). "Cardiac autonomic neuropathy in diabetes: a clinical perspective". Diabetes Care. 33 (2): 434–41. doi:10.2337/dc09-1294. PMC 2809298. PMID 20103559.
- ↑ McCarty N, Silverman B (2016). "Cardiovascular autonomic neuropathy". Proc (Bayl Univ Med Cent). 29 (2): 157–9. PMC 4790554. PMID 27034552.
- ↑ Bissinger A (2017). "Cardiac Autonomic Neuropathy: Why Should Cardiologists Care about That?". J Diabetes Res. 2017: 5374176. doi:10.1155/2017/5374176. PMC 5682059. PMID 29214181.
- ↑ Kenny GP, Sigal RJ, McGinn R (2016). "Body temperature regulation in diabetes". Temperature (Austin). 3 (1): 119–45. doi:10.1080/23328940.2015.1131506. PMC 4861190. PMID 27227101.
- ↑ Burakgazi AZ, Alsowaity B, Burakgazi ZA, Unal D, Kelly JJ (2012). "Bladder dysfunction in peripheral neuropathies". Muscle Nerve. 45 (1): 2–8. doi:10.1002/mus.22178. PMID 22190298.
- ↑ Tanik N, Tanik S, Albayrak S, Zengin K, Inan LE, Caglayan EK; et al. (2016). "Association Between Overactive Bladder and Polyneuropathy in Diabetic Patients". Int Neurourol J. 20 (3): 232–239. doi:10.5213/inj.1632508.254. PMC 5083825. PMID 27706007.
- ↑ DeMill DL, Hussain M, Pop-Busui R, Shtein RM (2016). "Ocular surface disease in patients with diabetic peripheral neuropathy". Br J Ophthalmol. 100 (7): 924–928. doi:10.1136/bjophthalmol-2015-307369. PMC 5037046. PMID 26500330.
- ↑ Srinivasan S, Pritchard N, Sampson GP, Edwards K, Vagenas D, Russell AW; et al. (2017). "Diagnostic capability of retinal thickness measures in diabetic peripheral neuropathy". J Optom. 10 (4): 215–225. doi:10.1016/j.optom.2016.05.003. PMC 5595257. PMID 27423690.
- ↑ Nightingale LM, Paviour DC (2009). "Nutritional optic and peripheral neuropathy: a case report". Cases J. 2: 7762. doi:10.4076/1757-1626-2-7762. PMC 2740016. PMID 19830009.