Thrombotic thrombocytopenic purpura risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Risk Factors
Common Risk Factors
Common risk factors in the development of TTP may be occupational, environmental, genetic, and viral.
Common risk factors in the development of TTP include:[1][2][3]
- Black ethnicity
- Female gender
- SLE
- Obesity
- Pregnancy (third trimester)
- Cancer therapies
Less Common Risk Factors
Less common risk factors in the development of TTP include:[4]
- HIV infection
- Bone marrow transplantation
- Antiplatelet agents
- Quinine
References
- ↑ Martino S, Jamme M, Deligny C, Busson M, Loiseau P, Azoulay E, Galicier L, Pène F, Provôt F, Dossier A, Saheb S, Veyradier A, Coppo P (2016). "Thrombotic Thrombocytopenic Purpura in Black People: Impact of Ethnicity on Survival and Genetic Risk Factors". PLoS ONE. 11 (7): e0156679. doi:10.1371/journal.pone.0156679. PMC 4934773. PMID 27383202.
- ↑ Nicol, Kathleen K.; Shelton, Brent J.; Knovich, Mary Ann; Owen, John (2003). "Overweight individuals are at increased risk for thrombotic thrombocytopenic purpura". American Journal of Hematology. 74 (3): 170–174. doi:10.1002/ajh.10418. ISSN 0361-8609.
- ↑ Scully M, Thomas M, Underwood M, Watson H, Langley K, Camilleri RS, Clark A, Creagh D, Rayment R, Mcdonald V, Roy A, Evans G, McGuckin S, Ni Ainle F, Maclean R, Lester W, Nash M, Scott R, O Brien P (July 2014). "Thrombotic thrombocytopenic purpura and pregnancy: presentation, management, and subsequent pregnancy outcomes". Blood. 124 (2): 211–9. doi:10.1182/blood-2014-02-553131. PMID 24859360.
- ↑ Visagie GJ, Louw VJ (August 2010). "Myocardial injury in HIV-associated thrombotic thrombocytopenic purpura (TTP)". Transfus Med. 20 (4): 258–64. doi:10.1111/j.1365-3148.2010.01006.x. PMID 20409074.